SPRING 2006
Biology of Neurological and Neuropsychiatric Diseases
Course Directors: Jacqueline F. McGinty, Ph.D., Kathleen Brady, M.D., Ph.D.,
Kenton R. Holden, M.D.

Library Room 405 Tues & Thurs 9-11AM
4 credits (4 hr per week over 16 weeks)

Syndrome
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Week 1-2: CNS Injury and Repair
    Introduction to the Course by Dr. McGinty Lecturer
January 3
T
 Stroke  
    - Acute Stroke (Updated with Chapters) Chalela
    - Pathophysiology of Stroke (Updated with Chapters) Kindy
January 5
Th
 CNS Injury Discussion and Journal Article Student
January 10
 T CNS Trauma: Spinal Cord Injury (Updated with Chapters) Banik / Krause
January 12
 Th

Epilepsy (Updated with Chapters)

 Holden / Escayg
Week 3-4: Disorders of the Motor System
January 17
 T Hyperkinetic Movement Disorders:
Huntington’s, Tourette’s, Dystonia (Updated with Chapters)		 Hinson / Chesselet
January 19
 Th Hypokinetic Movement Disorders: Parkinson's Disease
(Updated with Chapters)		 Bergmann/McGinty
January 24
 T Neuromuscular Disorders: Anterolateral Sclerosis  
    - Lessons from a Degenerative Illness (Updated with Chapters) Mackler
    - Motor Neuron Disease (Updated with Chapters) Stickler
January 26
 Th Inflammatory CNS Disorders: Multiple Sclerosis (Updated with Chapters)
 Tyor / Bhat
Week 5-7: Neuropsychiatric Disorders
January 31
 T Shizophrenia  
    - Neurobiology of Schizophrenia (Updated with Chapters) Lavin
    - Schizophrenia (Updated with Chapters) Holt
February 2
 Th Bipolar and Depression  
    - Neurobiology of Depression (Updated with Chapters) Nahas
 
- Cellular Neurobiology of Bipolar Disorder and Depression
(Updated with Chapters)		 Ramamoorthy
February 7
 T ADHD and OCD  
    - Clinical Presentation of ADHD and OCD (Updated with Chapters) Upadhyaya
    - Neurobiology of ADHD (Updated with Chapters) Lavin
February 9
 Th Stress and Anxiety Disorders (Updated with Chapters) Lydiard / Becker
February 14
 T Neuroimaging in Neuropsychiatry  
    - Brain Imaging in Neuropsychiatry (Updated with Chapters) George
    - Using MRI to Address Neuropsychiatric Questions Baylis
February 16
 Th Neuropsychiatric Disorders Discussion and Journal Article
 Student
Week 8-9: Addictive Disorders
February 21
 T Alcoholism  
    - Alcohol: Pharmacology and Neurobiology (Updated with Chapters) Becker
    - Advances in Addiction Neuroscience and Phamacotherapy of Alcoholism
(Updated with Chapters) 		Anton
February 23
 Th Stimulant Abuse
  
    - Overview of Stimulants (Updated with Chapters) Myrick
    - Stimulants (Updated with Chapters) Kalivas
February 28
 T Opiates  
    - Opiates (Updated with Chapters) See
    - Clinical Aspects of Opiates (Updated with Chapters) Malcolm
March 2
 Th Addictive Disorders Discussion and Journal Article
 Student
Week 10-11: Aging-Related Disorders
March 7
 T Alzheimer's Disease  
    - Alzheimer's Disease Sambamurti
    - Alzheimer's Disease Mintzer
March 9
 Th The Aging Nervous System  
    - Biology of Aging Granholm
    - Neurobiology of Aging: Cognitive Function Bachman
March 21
 T Drug Development for Neuropsychiatric Diseases  
    - Drug Development for Neuropsychiatric Diseases DeVane
    - Drug Development for Neuropsychiatric Diseases Sambamurti
March 23
 Th Aging Disorders Discussion and Journal Article
 Student
Week 12-13: Genetic/Developmental Disorders
March 28
 T Mental Retardation: Fragile X Syndrome  
    - Fragile X Syndrome Saul
    - Fragile X Syndrome Jin
March 30
 Th Genetic/Developmental Disorders Discussion and Journal Article Student Student
April 4
 T Pervasive Developmental Disorders: Autism/Asperger  
    - Understanding Autism Spectrum Disorders Charles
    - Translational Research Approaches for Stuying the Pathophysiology of Autism Levitt
April 6
 Th Mental Retardation: Down's Syndrome
  - Genetic Basis of Mental Retardation Pai
  - Down' Syndrome and Alzheimer's Disease: Is There a Connection? Granholm
Week 14-15: Ethical and Treatment Issues
April 11
 T Pain Management  
    - Pain Classification and Assessment Kurent
    - Chronic Pain Syndromes Brewer
April 13
 Th Gene Therapy and Stem Cell Initiatives  
    - Gene Therapy and Stem Cells: Reality, Hype or Hope Skinner
    - Stem Cells and Stem Cell Therapy Wei
April 18
 T Ethical Issues in Clinical Research  
    - Neurogenetics Ethics Lebel
    - Ethical Issues in Clinical Research McRae
April 20
 Th Discussion of Ethical and Treatment Issues
 Student
Week 16: Student Presentations
April 25
 T Student Oral Presentations  
April 27
 Th Student Oral Presentations
  

2007 Presentation Schedule